Circadin® has specific effects on sleep initiation and maintenance in elderly patients with primary insomnia, improving sleep quality and morning alertness. These are the pre-conditions for normal daily performance and productivity leading to higher quality of life. Circadin® is well tolerated and safe and does not lead to next days hangover effects or impairments of memory, cognitive skills, or daytime vigilance. Patients do not develop tolerance to Circadin® during prolonged periods of use and experience no withdrawal effects or rebound insomnia upon discontinuation. 

Circadin® is the preferred first line treatment of primary insomnia in the elderly because it proved efficacious and safe in phase III clinical trials. It is the only sleeping medication that received approval exclusively for the treatment of non-restorative sleep in patients with primary insomnia 55 and older.

 

Circadin® significantly improved sleep quality, morning alertness, and daytime functioning.

 

Circadin® has a significant and clinically relevant effect on sleep latency.

 

Circadin® singnificantly improves quality of life in patients suffering from non-restorative sleep.

 

Circadin® shows increased benefit for the population group aged 55 and older with primary insomnia.

Circadin® is safe in elder insomniacs at higher risk of falls and cognitive impairment.

 

Circadin® is safe in patients with cardiovascular abnormalities and diabetes patients.

 

Circadin® is safe with most prevalent co-medication.

 

Circadin® can be discontinued without withdrawal symptoms and is safe in overdose.
 

Circadin® presents a new treatment paradigm for insomnia being a formulation of melatonin maintaining the physiological sleep architecture.

 

Circadin® is the first insomnia drug prove to produce significant and clinically relevant improvement in sleep quality, morning alertness, and daytime functioning and consequently quality of live. Further, it has a significant and clinically relevant effect on sleep latency.

 

Circadin® is safe and well tolerate; its safety profile is highly favorable

 

Circadin® meets several so far "unmet medical needs" of insomnia treatment, mainly it demonstrates safety regarding  side effects, tolerance and dependency - which aer in the focus of physicians' and patient' concerns.